Low opsonic activity to the infecting serotype in pediatric patients with invasive pneumococcal disease

Highlights ► IgG and OI for the infecting serotype were tested in pediatric patients with IPD. ► IgG levels were higher than 0.2 μg/ml; OIs were

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Bibliographische Detailangaben
Veröffentlicht in:	Vaccine 2013-01, Vol.31 (5), p.845-849
Hauptverfasser:	Oishi, Tomohiro, Ishiwada, Naruhiko, Matsubara, Kousaku, Nishi, Junichiro, Chang, Bin, Tamura, Kazuyo, Akeda, Yukihiro, Ihara, Toshiaki, Nahm, Moon H, Oishi, Kazunori
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Antibiotics Antibodies, Bacterial - blood Antibody Affinity Applied microbiology Bacterial diseases Bacteriology Biological and medical sciences blood serum boys Child Child, Preschool Children Ear diseases Female Fundamental and applied biological sciences. Psychology Human bacterial diseases Humans immunity immunoglobulin G Immunoglobulin G - blood Infant Infectious diseases Invasive pneumococcal disease Male Medical sciences Meningitis Microbiology Miscellaneous Opsonin Proteins - blood Opsonophagocytic activity Patients Pneumococcal Infections - immunology Pneumococcal vaccine Pneumonia Serotype-specific IgG serotypes Staphylococcal infections, streptococcal infections, pneumococcal infections Streptococcus infections Streptococcus pneumoniae Streptococcus pneumoniae - immunology Vaccines Vaccines, antisera, therapeutical immunoglobulins and monoclonal antibodies (general aspects)
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Beschreibung
Zusammenfassung:	Highlights ► IgG and OI for the infecting serotype were tested in pediatric patients with IPD. ► IgG levels were higher than 0.2 μg/ml; OIs were
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2012.11.010