Extradural hematoma in Plasmodium vivax malaria: Are we alert to detect?

Peripheral blood smear was positive for Plasmodium vivax gametocytes and ring stages with marked parasitaemia and rapid card test was done to rule out undetected mixed infection, which is based on detecting specific Plasmodium LDH antigen by using monoclonal antibody directed against iso-forms of the enzyme. [8] When infected erythrocyte sequestrates, there is local production of lactate due to impaired tissue perfusion. [...]the cellular hypoxia increases the production of serum tumor necrosis factor-α (TNF-α), a potential immunogenetic marker, and vary with severity of disease.