Are Outcomes of Extremely Preterm Infants Improving? Impact of Bayley Assessment on Outcomes

Objectives To compare 18- to 22-month cognitive scores and neurodevelopmental impairment (NDI) in 2 time periods using the National Institute of Child Health and Human Development's Neonatal Research Network assessment of extremely low birth weight infants with the Bayley Scales of Infant Devel...

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Veröffentlicht in:	The Journal of pediatrics 2012-08, Vol.161 (2), p.222-228.e3
Hauptverfasser:	Vohr, Betty R., MD, Stephens, Bonnie E., MD, Higgins, Rosemary D., MD, Bann, Carla M., PhD, Hintz, Susan R., MD, MS Epi, Das, Abhik, PhD, Newman, Jamie E., PhD, MPH, Peralta-Carcelen, Myriam, MD, MPH, Yolton, Kimberly, PhD, Dusick, Anna M., MD, FAAP, Evans, Patricia W., MD, Goldstein, Ricki F., MD, Ehrenkranz, Richard A., MD, Pappas, Athina, MD, Adams-Chapman, Ira, MD, Wilson-Costello, Deanne E., MD, Bauer, Charles R., MD, Bodnar, Anna, MD, Heyne, Roy J., MD, Vaucher, Yvonne E., MD, MPH, Dillard, Robert G., MD, Acarregui, Michael J., MD, McGowan, Elisabeth C., MD, Myers, Gary J., MD, Fuller, Janell, MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cognition Developmental Disabilities - diagnosis General aspects Gestational Age Humans Infant Infant, Extremely Low Birth Weight Infant, Newborn Infant, Premature Infant, Premature, Diseases - physiopathology Language Development Medical sciences Neuropsychological Tests Pediatrics
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Zusammenfassung:	Objectives To compare 18- to 22-month cognitive scores and neurodevelopmental impairment (NDI) in 2 time periods using the National Institute of Child Health and Human Development's Neonatal Research Network assessment of extremely low birth weight infants with the Bayley Scales of Infant Development, Second Edition (Bayley II) in 2006-2007 (period 1) and using the Bayley Scales of Infant and Toddler Development, Third Edition (Bayley III), with separate cognitive and language scores, in 2008-2011 (period 2). Study design Scores were compared with bivariate analysis, and regression analyses were run to identify differences in NDI rates. Results Mean Bayley III cognitive scores were 11 points higher than mean Bayley II cognitive scores. The NDI rate was reduced by 70% (from 43% in period 1 to 13% in period 2; P < .0001). Multivariate analyses revealed that Bayley III contributed to a decreased risk of NDI by 5 definitions: cognitive score
ISSN:	0022-3476 1097-6833
DOI:	10.1016/j.jpeds.2012.01.057