Biomarker-enhanced triage in respiratory infections: a proof-of-concept feasibility trial

Concerns about inadequate performance and complexity limit routine use of clinical risk scores in lower respiratory tract infections. Our aim was to study feasibility and effects of adding the biomarker proadrenomedullin (proADM) to the confusion, urea>7 mmol·L(-1), respiratory rate≥30 breaths·mi...

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Veröffentlicht in:	The European respiratory journal 2013-10, Vol.42 (4), p.1064-1075
Hauptverfasser:	ALBRICH, Werner C, RÜEGGER, Kristina, GUGLIELMETTI, Merih, CONCA, Antoinette, SCHÄFER, Petra, SCHUBERT, Maria, DE GEEST, Sabina, REUTLINGER, Barbara, IRANI, Sarosh, BÜRGI, Ulrich, HUBER, Andreas, MÜLLER, Beat, DUSEMUND, Frank, SCHUETZ, Philipp, ARICI, Birsen, LITKE, Alexander, BLUM, Claudine A, BOSSART, Rita, REGEZ, Katharina, SCHILD, Ursula
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenomedullin - metabolism Adult Aged Algorithms Biological and medical sciences Biomarkers - metabolism Blood Pressure Feasibility Studies Female Hospitalization Humans Length of Stay Linear Models Male Medical sciences Middle Aged Original Pneumology Protein Precursors - metabolism Respiratory Tract Infections - metabolism Respiratory Tract Infections - physiopathology Risk Assessment Triage - methods
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Zusammenfassung:	Concerns about inadequate performance and complexity limit routine use of clinical risk scores in lower respiratory tract infections. Our aim was to study feasibility and effects of adding the biomarker proadrenomedullin (proADM) to the confusion, urea>7 mmol·L(-1), respiratory rate≥30 breaths·min(-1), blood pressure
ISSN:	0903-1936 1399-3003
DOI:	10.1183/09031936.00113612