Capture and Stimulated Release of Circulating Tumor Cells on Polymer-Grafted Silicon Nanostructures

A platform for capture and release of circulating tumor cells is demonstrated by utilizing polymer grafted silicon nanowires. In this platform, integration of ligand‐receptor recognition, nanostructure amplification, and thermal responsive polymers enables a highly efficient and selective capture of...

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Veröffentlicht in:	Advanced materials (Weinheim) 2013-03, Vol.25 (11), p.1547-1551
Hauptverfasser:	Hou, Shuang, Zhao, Haichao, Zhao, Libo, Shen, Qinglin, Wei, Kevin S., Suh, Daniel Y., Nakao, Aiko, Garcia, Mitch A., Song, Min, Lee, Tom, Xiong, Bin, Luo, Shyh-Chyang, Tseng, Hsian-Rong, Yu, Hsiao-hua
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrylic Resins - chemistry Antibodies - chemistry Antibodies - immunology Antigens, Neoplasm - chemistry Antigens, Neoplasm - immunology Biotin - chemistry Biotin - metabolism cancer diagnosis Cell Adhesion Molecules - chemistry Cell Adhesion Molecules - immunology cell capture Cell Line, Tumor cell release Cell Separation - instrumentation Cell Separation - methods Circulating circulating tumor cells Epithelial Cell Adhesion Molecule Humans MCF-7 Cells Nanocomposites Nanomaterials Nanostructure nanostructured materials Nanowires Nanowires - chemistry Neoplastic Cells, Circulating Platforms Polymers - chemistry Silicon Silicon - chemistry Streptavidin - chemistry Streptavidin - metabolism thermally responsive polymers Tumors
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