HIV Infection and Obesity: Where Did All the Wasting Go?

Background The success of antiretroviral therapy (ART) has led to dramatic changes in causes of morbidity and mortality in HIV-infected individuals. As chronic disease rates have increased in HIV-positive populations, modifiable risk factors such as obesity have increased in importance. Our objectiv...

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Veröffentlicht in:	Antiviral therapy 2012-01, Vol.17 (7), p.1281-1289
Hauptverfasser:	Tate, Tyler, Willig, Amanda L, Willig, James H, Raper, James L, Moneyham, Linda, Kempf, Mirjam-Colette, Saag, Michael S, Mugavero, Michael J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral agents Biological and medical sciences Body Mass Index CD4 Lymphocyte Count Female Follow-Up Studies HIV - genetics HIV - pathogenicity HIV Infections - drug therapy HIV Infections - epidemiology HIV Infections - pathology HIV Protease Inhibitors - adverse effects HIV Protease Inhibitors - therapeutic use Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Linear Models Male Medical sciences Metabolic diseases Middle Aged Obesity Obesity - chemically induced Obesity - epidemiology Overweight - chemically induced Overweight - epidemiology Pharmacology. Drug treatments Prevalence Risk Factors RNA, Viral - blood Time Factors Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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Zusammenfassung:	Background The success of antiretroviral therapy (ART) has led to dramatic changes in causes of morbidity and mortality in HIV-infected individuals. As chronic disease rates have increased in HIV-positive populations, modifiable risk factors such as obesity have increased in importance. Our objective was to evaluate factors associated with weight change among patients receiving ART. Methods ART-naive patients initiating therapy at the University of Alabama, Birmingham 1917 HIV/AIDS Clinic from 2000 to 2008 were included. Body mass index (BMI) was categorized as: underweight (
ISSN:	1359-6535 2040-2058
DOI:	10.3851/IMP2348