Acute Infection Induces a Metastatic Niche: A Double Menace for Cancer Patients
Tumor-derived factors can induce a premetastatic niche, yet little is known about how metastatic microenvironments are influenced by external insults, such as acute infections commonly seen in patients with cancer. New findings reveal increased metastasis to the lung after acute bacterial infection...
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| Veröffentlicht in: | Clinical cancer research 2013-09, Vol.19 (17), p.4547-4549 |
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| container_title | Clinical cancer research |
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| creator | SMITH, Heath A YIBIN KANG |
| description | Tumor-derived factors can induce a premetastatic niche, yet little is known about how metastatic microenvironments are influenced by external insults, such as acute infections commonly seen in patients with cancer. New findings reveal increased metastasis to the lung after acute bacterial infection via the CXCR4/ubiquitin axis, suggesting new targets for antimetastasis therapeutics. |
| doi_str_mv | 10.1158/1078-0432.CCR-13-1524 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1078-0432 |
| ispartof | Clinical cancer research, 2013-09, Vol.19 (17), p.4547-4549 |
| issn | 1078-0432 1557-3265 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3771332 |
| source | MEDLINE; American Association for Cancer Research; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Acute Lung Injury - genetics Animals Antineoplastic agents Biological and medical sciences Humans Lung Neoplasms - genetics Medical sciences Multiple tumors. Solid tumors. Tumors in childhood (general aspects) Pharmacology. Drug treatments Receptors, CXCR4 - genetics Tumors Ubiquitin - genetics |
| title | Acute Infection Induces a Metastatic Niche: A Double Menace for Cancer Patients |
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