Herpes Simplex Virus 1-Encoded Tegument Protein VP16 Abrogates the Production of Beta Interferon (IFN) by Inhibiting NF-κB Activation and Blocking IFN Regulatory Factor 3 To Recruit Its Coactivator CBP

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Veröffentlicht in:	Journal of Virology 2013-09, Vol.87 (17), p.9788-9801
Hauptverfasser:	Xing, Junji, Ni, Liwen, Wang, Shuai, Wang, Kezhen, Lin, Rongtuan, Zheng, Chunfu
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cercopithecus aethiops CREB-Binding Protein - metabolism HEK293 Cells HeLa Cells Herpes simplex virus 1 Herpes Simplex Virus Protein Vmw65 - chemistry Herpes Simplex Virus Protein Vmw65 - genetics Herpes Simplex Virus Protein Vmw65 - immunology Herpesvirus 1, Human - genetics Herpesvirus 1, Human - immunology Herpesvirus 1, Human - physiology Host-Pathogen Interactions - genetics Host-Pathogen Interactions - immunology Humans Immunity, Innate Interferon Regulatory Factor-3 - antagonists & inhibitors Interferon Regulatory Factor-3 - metabolism Interferon Regulatory Factor-7 - metabolism Interferon-beta - biosynthesis Interferon-beta - genetics Pathogenesis and Immunity Promoter Regions, Genetic Protein Structure, Tertiary Sendai virus Sendai virus - immunology Sendai virus - pathogenicity Transcription Factor RelA - antagonists & inhibitors Transcription Factor RelA - genetics Transcription Factor RelA - metabolism Transcriptional Activation Vero Cells
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Zusammenfassung:	Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue JVI About JVI Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy JVI RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0022-538X Online ISSN: 1098-5514 Copyright © 2014 by the American Society for Microbiology. For an alternate route to JVI .asm.org, visit: JVI
ISSN:	0022-538X 1098-5514
DOI:	10.1128/JVI.01440-13