Sleep quality and disease severity in patients with chronic rhinosinusitis

Objectives/Hypothesis To evaluate sleep quality in patients with chronic rhinosinusitis (CRS) using a validated outcome measure and to compare measures of CRS disease severity with sleep dysfunction. Study Design Cross‐sectional evaluation of a multi‐center cohort. Methods According to the 2007 Adult Sinusitis Guidelines, patients with CRS were prospectively enrolled from four academic, tertiary care centers across North America. Each subject completed the Pittsburgh Sleep Quality Index (PSQI) instrument, in addition to CRS‐specific measures of quality‐of‐life (QOL), endoscopy, computed tomography (CT), and olfaction. Patient demographics, comorbid conditions, and clinical measures of disease severity were compared between patients with “good” (PSQI; ≤5) and “poor” (PSQI; > 5) sleep quality. Results Patients (n = 268) reported a mean PSQI score of 9.4 (range: 0–21). Seventy‐five percent of patients reported PSQI scores above the traditional cutoff, indicating poor sleep quality. Patients with poor sleep quality were found to have significantly worse QOL scores on both the Rhinosinusitis Disability Index (P