Protection of human erythrocyte using Crinumasiaticum extract and lycorine from oxidative damage induced by 2-amidinopropane

The intention of this investigation was to evaluate the free radical scavenging activity and erythrocyte protective activity of ethanolic extract of Crinumasiaticum (L) and lycorine. The ethanolic extract of C. asiaticum (L) and lycorine were found to have different levels of antioxidant properties in the test models. Both ethanolic extract of C. asiaticum (L) (0.5–2.5mg/ml) and lycorine (0.010mg–0.050mg/ml) increases the percentage of lipid peroxidation inhibition (26.25±0.23% and 19.25±0.23%) and enhances the free radical scavenging activity (20.92±0.22% and 20.52±0.22%), scavenging of hydrogen peroxide (25.67±0.17% and 23.07±0.3%) superoxide anion scavenging activity (27.69±0.16% and 16.09±0.7%) at concentration of 2.5 and 0.050mg of C. asiaticum (L) and lycorine, respectively. But compared with tocopherol (P