Titan cells in Cryptococcus neoformans : cells with a giant impact

Highlights • Cryptococcus has an unusual morphological transition in vivo to generate enlarged titan cells. • Titan cells are greater than 15 μm in diameter, have a thick cell wall, and highly cross-linked capsule. • Titan cells are produced in both mammalian and invertebrate infections. • Titan cel...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Current opinion in microbiology 2013-08, Vol.16 (4), p.409-413
Hauptverfasser:	Zaragoza, Oscar, Nielsen, Kirsten
Format:	Artikel
Sprache:	eng
Schlagworte:	central nervous system Cryptococcus neoformans Cryptococcus neoformans - cytology Cryptococcus neoformans - pathogenicity Cryptococcus neoformans - physiology giant cells Host-Pathogen Interactions Humans immunocompromised population melanin Pathology virulence yeasts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Highlights • Cryptococcus has an unusual morphological transition in vivo to generate enlarged titan cells. • Titan cells are greater than 15 μm in diameter, have a thick cell wall, and highly cross-linked capsule. • Titan cells are produced in both mammalian and invertebrate infections. • Titan cells are important for cryptococcal pathogenesis.
ISSN:	1369-5274 1879-0364
DOI:	10.1016/j.mib.2013.03.006