Novel dimensions of piRNAs in cancer

Highlights • Piwi-interacting RNAs (piRNAs) may direct the Piwi-dependent biological functions. • piRNAs are the most mysterious class of small regulatory RNAs in tumorigenesis. • piRNAs may be disregulated and play crucial roles in tumorigenesis.

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Bibliographische Detailangaben
Veröffentlicht in:	Cancer letters 2013-08, Vol.336 (1), p.46-52
Hauptverfasser:	Mei, Yuping, Clark, David, Mao, Li
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Bias Biomarkers Biomarkers, Tumor Biosynthesis Cancer Diagnosis Epigenesis, Genetic Gastric cancer Gene Expression Regulation, Neoplastic Genes Hematology, Oncology and Palliative Medicine Humans Liver cancer Neoplasm Invasiveness Neoplasm Metastasis Neoplasms - genetics Neoplasms - metabolism PIWI-interacting RNAs Prognosis Proteins RNA, Small Interfering - genetics RNA, Small Interfering - metabolism Spermatogenesis Table tennis Therapy Transcription, Genetic Tumorigenesis
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Beschreibung
Zusammenfassung:	Highlights • Piwi-interacting RNAs (piRNAs) may direct the Piwi-dependent biological functions. • piRNAs are the most mysterious class of small regulatory RNAs in tumorigenesis. • piRNAs may be disregulated and play crucial roles in tumorigenesis.
ISSN:	0304-3835 1872-7980
DOI:	10.1016/j.canlet.2013.04.008