Antithrombotic therapies in patients with prosthetic heart valves: guidelines translated for the clinician

Patients with prosthetic heart valves require chronic oral anticoagulation. In this clinical scenario, physicians must be mindful of the thromboembolic and bleeding risks related to chronic anticoagulant therapy. Currently, only vitamin K antagonists are approved for this indication. This paper revi...

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Veröffentlicht in:	Journal of thrombosis and thrombolysis 2011-05, Vol.31 (4), p.514-522
Hauptverfasser:	Leiria, Tiago L. L., Lopes, Renato D., Williams, Judson B., Katz, Jason N., Kalil, Renato A. K., Alexander, John H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Anticoagulants - administration & dosage Anticoagulants - adverse effects Cardiology Fibrinolytic Agents - administration & dosage Fibrinolytic Agents - adverse effects Heart Valve Prosthesis Hematology Humans Medicine Medicine & Public Health Practice Guidelines as Topic Thromboembolism - prevention & control Vitamin K - antagonists & inhibitors
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Beschreibung
Zusammenfassung:	Patients with prosthetic heart valves require chronic oral anticoagulation. In this clinical scenario, physicians must be mindful of the thromboembolic and bleeding risks related to chronic anticoagulant therapy. Currently, only vitamin K antagonists are approved for this indication. This paper reviews the main heart valve guidelines focusing on the use of oral anticoagulation in these patients.
ISSN:	0929-5305 1573-742X
DOI:	10.1007/s11239-011-0574-9