Effect of micro-vibration culture system on embryo development

Purpose Micro-vibration culture system was examined to determine the effects on mouse and human embryo development and possible improvement of clinical outcomes in poor responders. Materials and methods The embryonic development rates and cell numbers of blastocysts were compared between a static culture group ( n = 178) and a micro-vibration culture group ( n = 181) in mice. The embryonic development rates and clinical results were compared between a static culture group ( n = 159 cycles) and a micro-vibration culture group ( n = 166 cycles) in poor responders. A micro-vibrator was set at a frequency of 42 Hz, 5 s/60 min duration for mouse and human embryo development. Results The embryonic development rate was significantly improved in the micro-vibration culture group in mice ( p