Phase separation in biological membranes: integration of theory and experiment

Phase separation in biological membranes: integration of theory and experiment

Lipid bilayer model membranes that contain a single lipid species can undergo transitions between ordered and disordered phases, and membranes that contain a mixture of lipid species can undergo phase separations. Studies of these transformations are of interest for what they can tell us about the i...

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Veröffentlicht in:Annual review of biophysics 2010-01, Vol.39 (1), p.207-226
Hauptverfasser: Elson, Elliot L, Fried, Eliot, Dolbow, John E, Genin, Guy M
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Humans
Lipid Bilayers - chemistry
Membrane Fluidity
Membrane Microdomains - chemistry
Thermodynamics
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Zusammenfassung:Lipid bilayer model membranes that contain a single lipid species can undergo transitions between ordered and disordered phases, and membranes that contain a mixture of lipid species can undergo phase separations. Studies of these transformations are of interest for what they can tell us about the interaction energies of lipid molecules of different species and conformations. Nanoscopic phases (
ISSN:1936-122X
1936-1238
DOI:10.1146/annurev.biophys.093008.131238