Emerging roles of actin cytoskeleton regulating enzymes in drug addiction: actin or reactin’?

Highlights ► Exposure to drugs of abuse causes changes in the cytoskeleton and neuronal structure. ► The explanations for and consequences of the changes remain elusive. ► Mutants in cytoskeletal regulatory genes alter drug-induced behavior.

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Bibliographische Detailangaben
Veröffentlicht in:	Current opinion in neurobiology 2013-08, Vol.23 (4), p.507-512
Hauptverfasser:	Rothenfluh, Adrian, Cowan, Christopher W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Central Nervous System - drug effects Central Nervous System - pathology Cocaine - pharmacology Cytoskeletal Proteins - genetics Cytoskeletal Proteins - metabolism Cytoskeleton - drug effects Ethanol - pharmacology Humans Neurology Psychiatry Street Drugs - pharmacology Substance-Related Disorders - drug therapy Substance-Related Disorders - metabolism Substance-Related Disorders - pathology
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Beschreibung
Zusammenfassung:	Highlights ► Exposure to drugs of abuse causes changes in the cytoskeleton and neuronal structure. ► The explanations for and consequences of the changes remain elusive. ► Mutants in cytoskeletal regulatory genes alter drug-induced behavior.
ISSN:	0959-4388 1873-6882
DOI:	10.1016/j.conb.2013.01.027