A Unified Synthetic Strategy to the Cryptocarya Family of Natural Products Exploiting Anion Relay Chemistry (ARC)
A unified synthetic strategy to the Cryptocarya family of natural products has been achieved employing four-component fragment unions in a “single flask” exploiting Anion Relay Chemistry (ARC). Functionalization of the ARC adducts permits rapid construction of five polyhydroxylated di- and tetrahydr...
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| Veröffentlicht in: | Organic letters 2013-05, Vol.15 (9), p.2282-2285 |
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| creator | Melillo, Bruno Smith, Amos B |
| description | A unified synthetic strategy to the Cryptocarya family of natural products has been achieved employing four-component fragment unions in a “single flask” exploiting Anion Relay Chemistry (ARC). Functionalization of the ARC adducts permits rapid construction of five polyhydroxylated di- and tetrahydropyrone natural products of the Cryptocarya class (1–5), in a total of 7–9 steps from commercially available materials. |
| doi_str_mv | 10.1021/ol400857k |
| format | Article |
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| ispartof | Organic letters, 2013-05, Vol.15 (9), p.2282-2285 |
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| language | eng |
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| source | MEDLINE; American Chemical Society Publications |
| subjects | Anions - chemistry Biological Products - chemistry chemical reactions chemical structure Combinatorial Chemistry Techniques Cryptocarya Cryptocarya - chemistry Molecular Structure organic compounds |
| title | A Unified Synthetic Strategy to the Cryptocarya Family of Natural Products Exploiting Anion Relay Chemistry (ARC) |
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