Rate of progression of CT-quantified emphysema in male current and ex-smokers: a follow-up study

Little is known about the factors associated with CT-quantified emphysema progression in heavy smokers. The objective of this study was to investigate the effect of length of smoking cessation and clinical / demographical factors on the rate of emphysema progression and FEV1-decline in male heavy sm...

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Veröffentlicht in:	Respiratory research 2013-05, Vol.14 (1), p.55-55
Hauptverfasser:	Mohamed Hoesein, Firdaus A A, Zanen, Pieter, de Jong, Pim A, van Ginneken, Bram, Boezen, H Marike, Groen, Harry J M, Oudkerk, Mathijs, de Koning, Harry J, Postma, Dirkje S, Lammers, Jan-Willem J
Format:	Artikel
Sprache:	eng
Schlagworte:	Chronic obstructive pulmonary disease Comorbidity Development and progression Diagnosis Disease Progression Emphysema Emphysema - diagnostic imaging Emphysema - epidemiology Emphysema, Pulmonary Ex-smokers Health aspects Humans Male Middle Aged Netherlands - epidemiology Prevalence Pulmonary function tests Risk Factors Severity of Illness Index Smoking - epidemiology Smoking cessation Smoking Cessation - statistics & numerical data Studies Tomography, X-Ray Computed - statistics & numerical data
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Zusammenfassung:	Little is known about the factors associated with CT-quantified emphysema progression in heavy smokers. The objective of this study was to investigate the effect of length of smoking cessation and clinical / demographical factors on the rate of emphysema progression and FEV1-decline in male heavy smokers. 3,670 male smokers with mean (SD) 40.8 (17.9) packyears underwent chest CT scans and pulmonary function tests at baseline and after 1 and 3 years follow-up. Smoking status (quitted ≥5, ≥1-
ISSN:	1465-9921 1465-993X 1465-993X 1465-9921
DOI:	10.1186/1465-9921-14-55