Base J: Blocking RNA Polymerase’s Way
How do cells stop transcribing RNA Polymerase II to promote proper gene expression and prevent transcriptional havoc in the genome? A uniquely modified DNA base in Leishmania blocks RNA Polymerase II and suggests an interesting new model for transcription termination.
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| Veröffentlicht in: | Current biology 2012-11, Vol.22 (22), p.R960-R962 |
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| Hauptverfasser: | , |
| Format: | Artikel |
| Sprache: | eng |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | How do cells stop transcribing RNA Polymerase II to promote proper gene expression and prevent transcriptional havoc in the genome? A uniquely modified DNA base in
Leishmania
blocks RNA Polymerase II and suggests an interesting new model for transcription termination. |
|---|---|
| ISSN: | 0960-9822 1879-0445 |
| DOI: | 10.1016/j.cub.2012.10.010 |