Diet-induced obesity causes long QT and reduces transcription of voltage-gated potassium channels

Abstract In humans, obesity is associated with long QT, increased frequency of premature ventricular complexes, and sudden cardiac death. The mechanisms of the pro-arrhythmic electrophysiologic remodeling of obesity are poorly understood. We tested the hypothesis that there is decreased expression o...

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Veröffentlicht in:Journal of molecular and cellular cardiology 2013-06, Vol.59, p.151-158
Hauptverfasser: Huang, Haiyan, Amin, Vaibhav, Gurin, Michael, Wan, Elaine, Thorp, Edward, Homma, Shunichi, Morrow, John P
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Sprache:eng
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