Glucose Variability: Where It Is Important and How to Measure It

Glucose Variability: Where It Is Important and How to Measure It

Glucose variability predicts hypoglycemia in both type 1 and type 2 diabetes and has consistently been related to mortality in nondiabetic patients in the intensive care unit. SD and mean amplitude of glycemic excursions have historically been very popular measures of glucose variability. For reason...

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Veröffentlicht in:Diabetes (New York, N.Y.) N.Y.), 2013-05, Vol.62 (5), p.1405-1408
1. Verfasser: DEVRIES, J. Hans
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Biological and medical sciences
Blood glucose
Blood Glucose - analysis
Blood sugar
Diabetes
Diabetes Complications - diagnosis
Diabetes Mellitus - blood
Diabetes. Impaired glucose tolerance
Endocrine pancreas. Apud cells (diseases)
Endocrinopathies
Etiopathogenesis. Screening. Investigations. Target tissue resistance
Glucose monitoring
Health aspects
Humans
Hyperglycemia
Hyperglycemia - blood
Hypoglycemia
Hypoglycemia - blood
Intensive care
Intensive Care Units
Investigations
Measurement
Medical sciences
Mortality
Oxidative stress
Point-Counterpoint
Postprandial Period
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Zusammenfassung:Glucose variability predicts hypoglycemia in both type 1 and type 2 diabetes and has consistently been related to mortality in nondiabetic patients in the intensive care unit. SD and mean amplitude of glycemic excursions have historically been very popular measures of glucose variability. For reasons outlined in this counterpoint, I propose to use coefficient of variation and the mean absolute glucose change as preferred measures of glucose variability.
ISSN:0012-1797
1939-327X
DOI:10.2337/db12-1610