Curcumin as an amyloid-indicator dye in E. coli

Curcumin as an amyloid-indicator dye in E. coli

We have demonstrated that curcumin is an amyloid-specific dye in E. coli. Curcumin binds to curliated whole cells and to isolated curli amyloid fibers. Similar to Congo red, curcumin exhibits a red-shift in absorbance and a significant increase in fluorescence upon binding to isolated curli.

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Veröffentlicht in:Chemical communications (Cambridge, England) England), 2013-01, Vol.49 (39), p.4193-4195
Hauptverfasser: McCrate, Oscar A, Zhou, Xiaoxue, Cegelski, Lynette
Format: Artikel
Sprache:eng
Schlagworte:
Amyloid - chemistry
Amyloid - metabolism
Benzenesulfonates - chemistry
Biofilms
Coloring Agents - chemistry
Congo Red - chemistry
Curcumin - chemistry
Escherichia coli - physiology
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Zusammenfassung:We have demonstrated that curcumin is an amyloid-specific dye in E. coli. Curcumin binds to curliated whole cells and to isolated curli amyloid fibers. Similar to Congo red, curcumin exhibits a red-shift in absorbance and a significant increase in fluorescence upon binding to isolated curli.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc37792f