CA19-9 elevation in ovarian mature cystic teratoma: discrimination from ovarian cancer - CA19-9 level in teratoma

We aimed to identify clinical characteristics of ovarian mature cystic teratoma (MCT) in association with CA19-9 elevation, and to determine if CA19-9 is a useful marker in discrimination of MCT from ovarian cancer (OC). Medical records of 322 women with pathologically-confirmed MCT or OC (stage 1 o...

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Veröffentlicht in:	Medical science monitor 2013-03, Vol.19, p.230-235
Hauptverfasser:	Cho, Hye-yon, Kim, Kidong, Jeon, Yong-Tark, Kim, Yong-Beom, No, Jae Hong
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over CA-125 Antigen - blood CA-19-9 Antigen - blood Clinical Research Diagnosis, Differential Female Humans Middle Aged Multivariate Analysis Ovarian Neoplasms - blood Ovarian Neoplasms - diagnosis Ovarian Neoplasms - pathology Teratoma - blood Teratoma - diagnosis Teratoma - pathology
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Zusammenfassung:	We aimed to identify clinical characteristics of ovarian mature cystic teratoma (MCT) in association with CA19-9 elevation, and to determine if CA19-9 is a useful marker in discrimination of MCT from ovarian cancer (OC). Medical records of 322 women with pathologically-confirmed MCT or OC (stage 1 or 2) were reviewed retrospectively. The relationships between the characteristics of MCT (mean diameter, bilaterality, and pathologic components) and elevated CA19-9 were evaluated. Tumor markers in MCT were compared to those in OC. MCTs with CA19-9 elevation were correlated with a larger diameter (8.53±3.84 cm vs. 6.95±3.97 cm, p=0.002) and presence of fat component (67.1% vs. 32.9%, p
ISSN:	1643-3750 1234-1010 1643-3750
DOI:	10.12659/MSM.883865