Encephalopathy secondary to isoniazid in patients on hemodialysis

Encephalopathy secondary to isoniazid in patients on hemodialysis

We report isoniazid (INH)-induced encephalopathy in two male patients on hemodialysis. One of them had tuberculous adenitis, and the other had pulmonary tuberculosis. Both were given rifampicin, INH, pyrazinamide, and ethambutol with pyridoxine 40 mg/day. Two patients developed disturbances in consc...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Indian journal of nephrology 2013-01, Vol.23 (1), p.54-56
Hauptverfasser: Abbas, M, Khan, F, Sulimon, S, Baidaa, A
Format: Artikel
Sprache:eng
Schlagworte:
Care and treatment
Case Report
Case studies
Diagnosis
Diseases
Drug therapy
Encephalopathy
Health aspects
Hemodialysis patients
Isoniazid
Kidney diseases
Medical examination
Neurological disorders
Patient outcomes
Risk factors
Side effects
Tuberculosis
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We report isoniazid (INH)-induced encephalopathy in two male patients on hemodialysis. One of them had tuberculous adenitis, and the other had pulmonary tuberculosis. Both were given rifampicin, INH, pyrazinamide, and ethambutol with pyridoxine 40 mg/day. Two patients developed disturbances in consciousness. After excluding other causes, INH-induced encephalopathy was suspected so the drug was stopped and dose of pyridoxine increased. Both patients retained their consciousness within 1 week and were discharged.
ISSN:0971-4065
1998-3662
DOI:10.4103/0971-4065.107206