Stem Cell Therapy for Lower Extremity Diabetic Ulcers: Where Do We Stand?

The impairment of wound healing in diabetic patients is an important clinical problem affecting millions of patients worldwide. Various clinical and basic science studies show that stem cell therapy, as a regenerative medical therapy, can be a good solution. In this paper, we begin with an introduct...

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Veröffentlicht in:	BioMed research international 2013-01, Vol.2013 (2013), p.1-8
Hauptverfasser:	Li, Qingfeng, Zhang, Tian R., Sheng, Lingling, Yang, Mei
Format:	Artikel
Sprache:	eng
Schlagworte:	Care and treatment Cell- and Tissue-Based Therapy Diabetes Complications - complications Diabetes Complications - pathology Diabetes Complications - therapy Diabetic Foot - complications Diabetic Foot - pathology Diabetic Foot - therapy Diabetic ulcers Diagnosis Humans Lower Extremity - pathology Neovascularization, Physiologic Review Stem Cell Transplantation Stem cells Transplantation Wound Healing
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Beschreibung
Zusammenfassung:	The impairment of wound healing in diabetic patients is an important clinical problem affecting millions of patients worldwide. Various clinical and basic science studies show that stem cell therapy, as a regenerative medical therapy, can be a good solution. In this paper, we begin with an introduction of the cellular mechanism of the diabetic ulcer. We will then discuss the advantages and limitations of various stem cell therapies that have been under extensive recent study.
ISSN:	2314-6133 2314-6141
DOI:	10.1155/2013/462179