Dietary selenium fails to influence cigarette smoke-induced lung tumorigenesis in A/J mice
Highlights • Higher dietary sodium selenite did not inhibit the induction of lung tumors. • Higher dietary selenium increased selenium and GPx protein levels in the lung. • Dietary selenium did not affect lung SOD levels.
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| Veröffentlicht in: | Cancer letters 2013-06, Vol.334 (1), p.127-132 |
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| container_end_page | 132 |
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| container_issue | 1 |
| container_start_page | 127 |
| container_title | Cancer letters |
| container_volume | 334 |
| creator | Glauert, Howard P Martin, Joshua B Li, Jun Tharappel, Job C Han, Sung Gu Gillespie, Harold D Cantor, Austin H Lee, Eun Y Gary Gairola, C |
| description | Highlights • Higher dietary sodium selenite did not inhibit the induction of lung tumors. • Higher dietary selenium increased selenium and GPx protein levels in the lung. • Dietary selenium did not affect lung SOD levels. |
| doi_str_mv | 10.1016/j.canlet.2012.11.047 |
| format | Article |
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| ispartof | Cancer letters, 2013-06, Vol.334 (1), p.127-132 |
| issn | 0304-3835 1872-7980 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3604161 |
| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Animals Anticarcinogenic Agents - pharmacology Antioxidant Carcinogenesis Cigarette smoke Cigarettes Diet Dietary Supplements Female Glutathione Peroxidase - metabolism Hematology, Oncology and Palliative Medicine Lung Lung - drug effects Lung - metabolism Lung cancer Lung Neoplasms - chemically induced Lung Neoplasms - metabolism Lung Neoplasms - prevention & control Mice, Inbred Strains Proliferating Cell Nuclear Antigen - metabolism Proteins Rodents Selenium Selenium - pharmacology Software Studies Superoxide Dismutase - metabolism Tobacco smoke Tobacco Smoke Pollution - adverse effects Tumorigenesis Tumors Variance analysis Vitamin E |
| title | Dietary selenium fails to influence cigarette smoke-induced lung tumorigenesis in A/J mice |
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