Kaposi sarcoma-associated herpesvirus g protein-coupled receptor enhances endothelial cell survival in part by upregulation of bcl-2

Kaposi sarcoma-associated herpesvirus (KSHV) encoded G protein-coupled receptor (vGPCR) is a constitutively active lytic phase protein with significant homology to the human interleukin-8 receptor. vGPCR is necessary and sufficient to induce angiogenesis as well as the spindle cell proliferation cha...

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Veröffentlicht in:The Ochsner journal 2013, Vol.13 (1), p.66-75
Hauptverfasser: Abboud, Elizabeth R, Shelby, Bryan D, Angelova, Magdalena, Nelson, Anne B, Ferris, Marybeth, McFerrin, Harris E, Morris, Cindy A, Sullivan, Deborah E
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Sprache:eng
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