Ventilatory responses during and following exposure to a hypoxic challenge in conscious mice deficient or null in S-nitrosoglutathione reductase
Highlights ► Initial ventilatory responses to hypoxic challenge were similar in WT and GSNOR deficient mice. ► Ventilatory roll-off occurred during hypoxic challenge in WT but not in GSNOR deficient mice. ► Post-hypoxia responses were greater in female GSNOR deficient mice than in female WT mice....
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Veröffentlicht in: | Respiratory physiology & neurobiology 2013-02, Vol.185 (3), p.571-581 |
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Hauptverfasser: | , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | Highlights ► Initial ventilatory responses to hypoxic challenge were similar in WT and GSNOR deficient mice. ► Ventilatory roll-off occurred during hypoxic challenge in WT but not in GSNOR deficient mice. ► Post-hypoxia responses were greater in female GSNOR deficient mice than in female WT mice. |
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ISSN: | 1569-9048 1878-1519 |
DOI: | 10.1016/j.resp.2012.11.009 |