Efficacy of a Non-Hormonal Treatment, BRN-01, on Menopausal Hot Flashes: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial

Background Homeopathic medicines have a place among the non-hormonal therapies for the treatment of hot flashes during the menopause. Objective The objective of this study was to evaluate the efficacy of the non-hormonal treatment BRN-01 in reducing hot flashes in menopausal women. Study Design This was a multicenter, randomized, double-blind, placebo-controlled study carried out between June 2010 and July 2011. Setting The study was conducted in 35 active centers in France (gynecologists in private practice). Patients One hundred and eight menopausal women, ≥50 years of age, were enrolled in the study. The eligibility criteria included menopause for