Are BDNF and glucocorticoid activities calibrated?

Graphical abstract The schematic is modified from Martin and Finsterwald (Commun Integr Biol. 4, 14–16, 2011). Highlights • Glucocorticoid oscillations enhance dendritic spine plasticity. • Disruption of glucocorticoid rhythms precipitates neurological disorders. • Normalization of glucocorticoid rh...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neuroscience 2013-06, Vol.239, p.173-195
Hauptverfasser:	Jeanneteau, F, Chao, M.V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain - metabolism Brain-Derived Neurotrophic Factor - metabolism dendritic spine endocrine FKBP5 glucocorticoid resistance Glucocorticoids - metabolism Humans MKP-1 Neurology Neuronal Plasticity - physiology Neurons - metabolism plasticity rhythms Signal Transduction - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Graphical abstract The schematic is modified from Martin and Finsterwald (Commun Integr Biol. 4, 14–16, 2011). Highlights • Glucocorticoid oscillations enhance dendritic spine plasticity. • Disruption of glucocorticoid rhythms precipitates neurological disorders. • Normalization of glucocorticoid rhythms is possible with antidepressants. • BDNF mediates the effects of antidepressants. • Are BDNF and glucocorticoid activities calibrated?
ISSN:	0306-4522 1873-7544 1873-7544
DOI:	10.1016/j.neuroscience.2012.09.017