MORC proteins and epigenetic regulation

Two recent studies in Arabidopsis implicated MORC proteins, which contain a GHKL ATPase domain, in transcriptional gene silencing. Here, these studies are compared and contrasted to discuss the roles of MORC proteins in epigenetic regulation. Although MORC proteins are likely to catalyze changes in...

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Veröffentlicht in:	Plant signaling & behavior 2012-12, Vol.7 (12), p.1561-1565
1. Verfasser:	Lorković, Zdravko J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphatases - genetics Adenosine Triphosphatases - metabolism Arabidopsis - genetics Arabidopsis - metabolism Arabidopsis Proteins - genetics Arabidopsis Proteins - metabolism DNA Methylation - genetics Epigenesis, Genetic - genetics Gene Expression Regulation, Plant - genetics Gene Expression Regulation, Plant - physiology Gene Silencing Short Communication
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Beschreibung
Zusammenfassung:	Two recent studies in Arabidopsis implicated MORC proteins, which contain a GHKL ATPase domain, in transcriptional gene silencing. Here, these studies are compared and contrasted to discuss the roles of MORC proteins in epigenetic regulation. Although MORC proteins are likely to catalyze changes in chromatin structure in response to epigenetic signals, their precise mode of action and target site-specificity still remain unclear.
ISSN:	1559-2316 1559-2324 1559-2324
DOI:	10.4161/psb.22460