Oscillations and hippocampal–prefrontal synchrony

Highlights ► Coherent oscillations are observed across the hippocampus and medial prefrontal cortex (mPFC). ► Hippocampal theta oscillations modulate mPFC during goal-directed behaviors and working memory. ► Bursts of mPFC gamma oscillations, phase-locked to hippocampal theta, may also subserve such...

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Veröffentlicht in:Current opinion in neurobiology 2011-06, Vol.21 (3), p.467-474
1. Verfasser: Colgin, Laura Lee
Format: Artikel
Sprache:eng
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Zusammenfassung:Highlights ► Coherent oscillations are observed across the hippocampus and medial prefrontal cortex (mPFC). ► Hippocampal theta oscillations modulate mPFC during goal-directed behaviors and working memory. ► Bursts of mPFC gamma oscillations, phase-locked to hippocampal theta, may also subserve such tasks. ► Hippocampal sharp waves and mPFC spindles may promote transfer of memories from hippocampus to mPFC. ► Oscillatory phase-locking between hippocampus and mPFC may be disrupted during schizophrenia.
ISSN:0959-4388
1873-6882
DOI:10.1016/j.conb.2011.04.006