Six-Month Hemoglobin Concentration and Its Association With Subsequent Mortality Among Adults on Antiretroviral Therapy in Lusaka, Zambia

Little is known about changes in hemoglobin concentration early in the course of antiretroviral therapy and its subsequent relation to survival. We analyzed data for 40,410 HIV-infected adults on antiretroviral therapy in Lusaka, Zambia. Our main exposure of interest was 6-month hemoglobin, but we s...

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Veröffentlicht in:	Journal of acquired immune deficiency syndromes (1999) 2012-09, Vol.61 (1), p.120-123
Hauptverfasser:	Giganti, Mark J, Limbada, Mohammed, Mwango, Albert, Moyo, Crispin, Mulenga, Lloyd B, Guffey, M Brad, Mulenga, Priscilla L, Bolton-Moore, Carolyn, Stringer, Jeffrey S A, Chi, Benjamin H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult AIDS/HIV Anemia Anemia - epidemiology Anemia - mortality Anti-Retroviral Agents - administration & dosage Antiretroviral drugs Antiretroviral Therapy, Highly Active - methods Biological and medical sciences Drug therapy Female Fundamental and applied biological sciences. Psychology Health hazards Hemoglobin Hemoglobins - analysis HIV HIV Infections - complications HIV Infections - drug therapy HIV Infections - mortality Human immunodeficiency virus Human viral diseases Humans Indexing in process Infectious diseases Male Medical sciences Microbiology Miscellaneous Mortality Survival Analysis Viral diseases Virology Zambia
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Zusammenfassung:	Little is known about changes in hemoglobin concentration early in the course of antiretroviral therapy and its subsequent relation to survival. We analyzed data for 40,410 HIV-infected adults on antiretroviral therapy in Lusaka, Zambia. Our main exposure of interest was 6-month hemoglobin, but we stratified our analysis by baseline hemoglobin to allow for potential effect modification. Patients with a 6-month hemoglobin
ISSN:	1525-4135 1944-7884
DOI:	10.1097/QAI.0b013e31825da11d