Effect of Menses on Clearance of Y-Chromosome in Vaginal Fluid: Implications for a Biomarker of Recent Sexual Activity

Self-reported sexual behaviors are subject to bias. We previously developed a polymerase chain reaction for the detection of Y-chromosome sequences in vaginal fluid as a potential biomarker of recent sexual activity. In this study, we found menses results in lower Y-chromosome concentrations but wit...

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Veröffentlicht in:	Sexually transmitted diseases 2010-01, Vol.37 (1), p.1-4
Hauptverfasser:	Brotman, Rebecca M., Melendez, Johan H., Smith, Tukisa D., Galai, Noya, Zenilman, Jonathan M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biological and medical sciences Biomarkers Case-Control Studies Chromosomes Chromosomes, Human, Y - physiology Coitus Epidemiology. Vaccinations Female General aspects Human infectious diseases. Experimental studies and models Humans Infectious diseases Medical sciences Menstruation Menstruation - physiology Polymerase Chain Reaction Sensitivity and Specificity Sexual behavior Sexually Transmitted Diseases - prevention & control Studies Vagina - physiology Vaginal Smears
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Beschreibung
Zusammenfassung:	Self-reported sexual behaviors are subject to bias. We previously developed a polymerase chain reaction for the detection of Y-chromosome sequences in vaginal fluid as a potential biomarker of recent sexual activity. In this study, we found menses results in lower Y-chromosome concentrations but with similar decay patterns as non-menstrual samples.
ISSN:	0148-5717 1537-4521
DOI:	10.1097/olq.0b013e3181b5f15d