Regio- and Stereoselective Synthesis of Cyclic Imidates via Electrophilic Cyclization of 2‑(1-Alkynyl)benzamides. A Correction

The electrophilic cyclization of 2-(1-alkynyl)benzamides affords high yields of cyclic imidates, instead of the previously reported isoindolin-1-ones, where cyclization proceeds on the oxygen of the carbonyl group rather than the nitrogen of the amide functionality. X-ray crystallography and spectro...

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Veröffentlicht in:Journal of organic chemistry 2012-12, Vol.77 (23), p.10938-10944
Hauptverfasser: Mehta, Saurabh, Yao, Tuanli, Larock, Richard C
Format: Artikel
Sprache:eng
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Zusammenfassung:The electrophilic cyclization of 2-(1-alkynyl)benzamides affords high yields of cyclic imidates, instead of the previously reported isoindolin-1-ones, where cyclization proceeds on the oxygen of the carbonyl group rather than the nitrogen of the amide functionality. X-ray crystallography and spectroscopic techniques have been used to characterize the products. A correction is hereby provided in order to rectify the previous misassignment of structure.
ISSN:0022-3263
1520-6904
DOI:10.1021/jo301958q