Modeling Rett Syndrome with Stem Cells

The discovery that somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) raised the exciting possibility of modeling diseases with patient-specific cells. Marchetto et al. (2010) now use iPSC technology to generate, characterize, and treat an in vitro model for the autism spe...

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Veröffentlicht in:Cell 2010-11, Vol.143 (4), p.499-500
Hauptverfasser: Walsh, Ryan M., Hochedlinger, Konrad
Format: Artikel
Sprache:eng
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Zusammenfassung:The discovery that somatic cells can be reprogrammed into induced pluripotent stem cells (iPSCs) raised the exciting possibility of modeling diseases with patient-specific cells. Marchetto et al. (2010) now use iPSC technology to generate, characterize, and treat an in vitro model for the autism spectrum disorder Rett syndrome.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2010.10.037