Asymptomatic Left Ventricular Systolic Dysfunction in Patients With Severe Aortic Stenosis: Characteristics and Outcomes

Asymptomatic Left Ventricular Systolic Dysfunction in Patients With Severe Aortic Stenosis: Characteristics and Outcomes

This study sought to determine the prevalence, characteristics, and outcomes of asymptomatic left ventricular (LV) systolic dysfunction in patients with severe aortic stenosis (AS). Management of asymptomatic patients with severe AS remains controversial. In these patients, LV systolic dysfunction,...

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Veröffentlicht in:Journal of the American College of Cardiology 2012-12, Vol.60 (22), p.2325-2329
Hauptverfasser: HENKEL, Danielle M, MALOUF, Joseph F, CONNOLLY, Heidi M, MICHELENA, Hector I, SARANO, Maurice E, SCHAFF, Hartzell V, SCOTT, Christopher G, PELLIKKA, Patricia A
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Aged, 80 and over
Aortic Valve Stenosis - epidemiology
Aortic Valve Stenosis - mortality
Aortic Valve Stenosis - physiopathology
Asymptomatic Diseases - epidemiology
Asymptomatic Diseases - mortality
Biological and medical sciences
Cardiology. Vascular system
Cohort Studies
Endocardial and cardiac valvular diseases
Female
Follow-Up Studies
Heart
Heart failure, cardiogenic pulmonary edema, cardiac enlargement
Heart Failure, Systolic - epidemiology
Heart Failure, Systolic - mortality
Heart Failure, Systolic - physiopathology
Humans
Male
Medical sciences
Middle Aged
Retrospective Studies
Severity of Illness Index
Survival Rate - trends
Treatment Outcome
Ventricular Dysfunction, Left - epidemiology
Ventricular Dysfunction, Left - mortality
Ventricular Dysfunction, Left - physiopathology
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Beschreibung
Zusammenfassung:This study sought to determine the prevalence, characteristics, and outcomes of asymptomatic left ventricular (LV) systolic dysfunction in patients with severe aortic stenosis (AS). Management of asymptomatic patients with severe AS remains controversial. In these patients, LV systolic dysfunction, defined in the guidelines as ejection fraction 40 mm Hg, aortic valve area [AVA]
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2012.08.988