The Role of Radiotherapy and Chemotherapy in the Treatment of Primary Adult High Grade Gliomas : Assessment of Patients for These Treatment Approaches and the Common Immediate Side Effects

Gliomas are the commonest primary brain tumours in adults. They are usually classified and graded according to the criteria by the World Health Organisation. High-grade gliomas are the most malignant primary brain tumours. Conventional therapies include surgery, radiotherapy, and chemotherapy. The tumours often demonstrate high levels of resistance to these conventional therapies, and in spite of treatment advances the prognosis remains poor.