Assessment of Anticholinesterase Activity of Gelidiella acerosa: Implications for Its Therapeutic Potential against Alzheimer’s Disease

Assessment of Anticholinesterase Activity of Gelidiella acerosa: Implications for Its Therapeutic Potential against Alzheimer’s Disease

The effect of various solvent extracts of Gelidiella acerosa on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities was investigated. AChE and BuChE inhibitory activities were analyzed by spectrophotometric method. Phytochemical screening of the compounds present in the solvent...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Evidence-based complementary and alternative medicine 2012-01, Vol.2012 (2012), p.1-8
Hauptverfasser: Syad, Arif Nisha, Kasi, Pandima Devi, Karutha Pandian, Shunmugiah
Format: Artikel
Sprache:eng
Schlagworte:
Acetylcholinesterase
Algae
Alzheimer's disease
Animal cognition
Antioxidants
Benzene
Brain research
Cholinesterase
Cholinesterase inhibitors
Coasts
Enzymes
Gelidiella acerosa
Inhibition
Laboratories
Pharmaceuticals
Phytochemicals
Spectrophotometry
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The effect of various solvent extracts of Gelidiella acerosa on acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) activities was investigated. AChE and BuChE inhibitory activities were analyzed by spectrophotometric method. Phytochemical screening of the compounds present in the solvent extracts was done qualitatively. Characterization of the compounds present in the benzene extract of G. acerosa was done by GC-MS analysis. The results showed that, at 487.80 μg/mL, benzene extract showed significant (P
ISSN:1741-427X
1741-4288
DOI:10.1155/2012/497242