Multiplexed Protein Arrays Enabled by Polymer Pen Lithography: Addressing the Inking Challenge

High‐end printer: A novel way of using a polymer pen lithography (PPL) array mould to localize different inks on the pens of a PPL array has been developed. This technique allows for rapid pen inking and subsequent generation of multiplexed patterns of up to 150 000 nano‐ and microscale protein feat...

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Veröffentlicht in:Angewandte Chemie (International ed.) 2009-01, Vol.48 (41), p.7626-7629
Hauptverfasser: Zheng, Zijian, Daniel, Weston L, Giam, Louise R, Huo, Fengwei, Senesi, Andrew J, Zheng, Gengfeng, Mirkin, Chad A
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Sprache:eng
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Zusammenfassung:High‐end printer: A novel way of using a polymer pen lithography (PPL) array mould to localize different inks on the pens of a PPL array has been developed. This technique allows for rapid pen inking and subsequent generation of multiplexed patterns of up to 150 000 nano‐ and microscale protein features per second (see picture). It is a general approach, which in principle can be extended to any substance that can be transported by PPL.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.200902649