The pathogenesis of systemic lupus erythematosus—an update

Highlights ► Innate effectors are critical for the lupus phenotype. ► Aberrant adaptive immune responses promote disease progression in SLE. ► Dissection of pathogenic events in SLE offers new therapeutic targets in SLE.

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Bibliographische Detailangaben
Veröffentlicht in:	Current opinion in immunology 2012-12, Vol.24 (6), p.651-657
Hauptverfasser:	Choi, Jinyoung, Kim, Sang Taek, Craft, Joe
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Autoantibodies - immunology Autoimmunity - physiology B-Lymphocytes - immunology Humans Immunity, Innate Lupus Erythematosus, Systemic - etiology T-Lymphocytes - immunology
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Highlights ► Innate effectors are critical for the lupus phenotype. ► Aberrant adaptive immune responses promote disease progression in SLE. ► Dissection of pathogenic events in SLE offers new therapeutic targets in SLE.
ISSN:	0952-7915 1879-0372
DOI:	10.1016/j.coi.2012.10.004