Risk Factors for the Hemolytic Uremic Syndrome in Children Infected With Escherichia coli O157:H7: A Multivariable Analysis

Risk Factors for the Hemolytic Uremic Syndrome in Children Infected With Escherichia coli O157:H7: A Multivariable Analysis

Background. Escherichia coli O157:H7 is the leading cause of hemolytic uremic syndrome (HUS). Risk factors for development of this complication warrant identification. Methods. We enrolled children infected with E. coli O157:H7 within 1 week of the onset of diarrhea in this prospective cohort study....

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Veröffentlicht in:Clinical infectious diseases 2012-07, Vol.55 (1), p.33-41
Hauptverfasser: Wong, Craig S., Mooney, Jody C., Brandt, John R., Staples, Amy O., Jelacic, Srdjan, Boster, Daniel R., Watkins, Sandra L., Tarr, Phillip I.
Format: Artikel
Sprache:eng
Schlagworte:
Age
and Commentaries
Anti-Bacterial Agents - therapeutic use
Antibiotics
ARTICLES AND COMMENTARIES
Biological and medical sciences
Child
Child, Preschool
Children
Childrens health
Complications
Diarrhea
Diseases
E coli
Escherichia coli
Escherichia coli Infections - complications
Escherichia coli Infections - drug therapy
Escherichia coli Infections - epidemiology
Escherichia coli O157 - isolation & purification
Female
Hematologic and hematopoietic diseases
Hemolytic uremic syndrome
Hemolytic-Uremic Syndrome - epidemiology
Hemolytic-Uremic Syndrome - microbiology
Humans
Infant
Infant, Newborn
Infection
Infections
Infectious diseases
Leukocyte Count
Leukocytes
Logistic Models
Male
Medical sciences
Medical treatment
Multivariate Analysis
Nephrology. Urinary tract diseases
Nephropathies. Renovascular diseases. Renal failure
Oliguria - epidemiology
Platelet diseases and coagulopathies
Predisposing factors
Renal failure
Retrospective Studies
Risk Factors
Vomiting
Vomiting - microbiology
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Zusammenfassung:Background. Escherichia coli O157:H7 is the leading cause of hemolytic uremic syndrome (HUS). Risk factors for development of this complication warrant identification. Methods. We enrolled children infected with E. coli O157:H7 within 1 week of the onset of diarrhea in this prospective cohort study. The study was conducted in 5 states over 9.5 years. The primary and secondary outcomes were HUS (hematocrit
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/cis299