Mini-haplotypes as lineage informative SNPs and ancestry inference SNPs

We propose that haplotyped loci with high heterozygosity can be useful in human identification, especially within families, if recombination is very low among the sites. Three or more SNPs extending over small molecular intervals (

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Bibliographische Detailangaben
Veröffentlicht in:	European journal of human genetics : EJHG 2012-11, Vol.20 (11), p.1148-1154
Hauptverfasser:	PAKSTIS, Andrew J, RIXUN FANG, FURTADO, Manohar R, KIDD, Judith R, KIDD, Kenneth K
Format:	Artikel
Sprache:	eng
Schlagworte:	Alleles Biological and medical sciences Deoxyribonucleic acid DNA Forensic science Forensic sciences Fundamental and applied biological sciences. Psychology Genealogy Genetics of eukaryotes. Biological and molecular evolution Genome, Human Genomes Haplotypes Heterozygosity Heterozygote Humans Indexing in process Internet resources Linkage Disequilibrium Medical genetics Medical sciences Medicine Molecular and cellular biology Mutation Polymorphism Polymorphism, Single Nucleotide Population Population Groups - genetics Recombinants Recombination Recombination, Genetic Single-nucleotide polymorphism
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Beschreibung
Zusammenfassung:	We propose that haplotyped loci with high heterozygosity can be useful in human identification, especially within families, if recombination is very low among the sites. Three or more SNPs extending over small molecular intervals (
ISSN:	1018-4813 1476-5438
DOI:	10.1038/ejhg.2012.69