Gold nanoparticles as novel agents for cancer therapy
Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers. This review introduces the field of nanotechnology with a focus on recent gold nanoparticle research which has led to early-p...
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| Veröffentlicht in: | British journal of radiology 2012-02, Vol.85 (1010), p.101-113 |
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| container_end_page | 113 |
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| container_issue | 1010 |
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| container_title | British journal of radiology |
| container_volume | 85 |
| creator | JAIN, S HIRST, D. G O'SULLIVAN, J. M |
| description | Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers. This review introduces the field of nanotechnology with a focus on recent gold nanoparticle research which has led to early-phase clinical trials. In particular, the pre-clinical evidence for gold nanoparticles as sensitisers with ionising radiation in vitro and in vivo at kilovoltage and megavoltage energies is discussed. |
| doi_str_mv | 10.1259/bjr/59448833 |
| format | Article |
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G</creatorcontrib><creatorcontrib>O'SULLIVAN, J. M</creatorcontrib><title>Gold nanoparticles as novel agents for cancer therapy</title><title>British journal of radiology</title><addtitle>Br J Radiol</addtitle><description>Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers. This review introduces the field of nanotechnology with a focus on recent gold nanoparticle research which has led to early-phase clinical trials. 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M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Gold nanoparticles as novel agents for cancer therapy</atitle><jtitle>British journal of radiology</jtitle><addtitle>Br J Radiol</addtitle><date>2012-02-01</date><risdate>2012</risdate><volume>85</volume><issue>1010</issue><spage>101</spage><epage>113</epage><pages>101-113</pages><issn>0007-1285</issn><eissn>1748-880X</eissn><coden>BJRAAP</coden><abstract>Gold nanoparticles are emerging as promising agents for cancer therapy and are being investigated as drug carriers, photothermal agents, contrast agents and radiosensitisers. This review introduces the field of nanotechnology with a focus on recent gold nanoparticle research which has led to early-phase clinical trials. 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| ispartof | British journal of radiology, 2012-02, Vol.85 (1010), p.101-113 |
| issn | 0007-1285 1748-880X |
| language | eng |
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| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Animals Biological and medical sciences Contrast Media - administration & dosage Drug Carriers - administration & dosage Gold - pharmacology Gold - therapeutic use Humans Hyperthermia, Induced - methods Investigative techniques, diagnostic techniques (general aspects) Magnetic Resonance Imaging - methods Medical sciences Metal Nanoparticles - therapeutic use Mice Models, Biological Neoplasms - therapy Plasmids - drug effects Radiation-Sensitizing Agents - administration & dosage Radiation-Sensitizing Agents - pharmacology Review Tomography, X-Ray Computed - methods |
| title | Gold nanoparticles as novel agents for cancer therapy |
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