Age and facial nerve axotomy-induced T cell trafficking: Relation to microglial and motor neuron status
Research highlights ► More CD3+ T cell in the injured FMN in 52-week-old mice than 8-week-old mice. ► Differences in CD11b+ clusters between 8- and 52-week-old mice in the injured FMN. ► Cumulative neuronal loss did not differ between 8- and 52-week-old mice. ► There was a small reduction in the siz...
Gespeichert in:
| Veröffentlicht in: | Brain, behavior, and immunity behavior, and immunity, 2011-01, Vol.25 (1), p.77-82 |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 82 |
|---|---|
| container_issue | 1 |
| container_start_page | 77 |
| container_title | Brain, behavior, and immunity |
| container_volume | 25 |
| creator | Dauer, Daniel J Huang, Zhi Ha, Grace K Kim, Jeremy Khosrowzadeh, David Petitto, John M |
| description | Research highlights ► More CD3+ T cell in the injured FMN in 52-week-old mice than 8-week-old mice. ► Differences in CD11b+ clusters between 8- and 52-week-old mice in the injured FMN. ► Cumulative neuronal loss did not differ between 8- and 52-week-old mice. ► There was a small reduction in the size of the surviving motor neurons in older mice. |
| doi_str_mv | 10.1016/j.bbi.2010.08.005 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3468329</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0889159110004307</els_id><sourcerecordid>858422268</sourcerecordid><originalsourceid>FETCH-LOGICAL-c537t-dcc17727ec0e9c3fa0b5c962d1073d9a4952ba5a26197225cce5d5d66b5d02823</originalsourceid><addsrcrecordid>eNqFkk1v1DAQhi0EosvCD-CCcuOUxR9xEoNUqar4kiohQTmPHHsSvE3sYicr9t_jaEsFHOBkjeedVzPzDCHPGd0xyupX-13XuR2nOabtjlL5gGwYVbTkTKiHZEPbVpVMKnZGnqS0p1khWPuYnHHa8EbV1YYMFwMW2tui18bpsfAYD_njR5jDdCydt4tBW1wXBsexmKPue2dunB9eF59x1LMLvphDMTkTwzCuBqvXlKtjtlpiTqdZz0t6Sh71ekz47O7dkq_v3l5ffiivPr3_eHlxVRopmrm0xrAm94aGojKi17STRtXcMtoIq3SlJO-01LxmquFcGoPSSlvXnbSUt1xsyfnJ93bpJrQGfW56hNvoJh2PELSDPzPefYMhHEBUdSu4ygYv7wxi-L5gmmFyaZ1eewxLgla2Fec8i_-rZJzxWkmRleykzFtKKWJ_3w-jsJKEPWSSsJIE2sLKaUte_D7IfcUvdFnw5iTAvM6DwwjJOPQZl4toZrDB_dP-_K9qMzrvjB5v8IhpH5boMydgkDhQ-LKe0npJLB9RJTKMnxo2xNI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>812126953</pqid></control><display><type>article</type><title>Age and facial nerve axotomy-induced T cell trafficking: Relation to microglial and motor neuron status</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals Complete</source><creator>Dauer, Daniel J ; Huang, Zhi ; Ha, Grace K ; Kim, Jeremy ; Khosrowzadeh, David ; Petitto, John M</creator><creatorcontrib>Dauer, Daniel J ; Huang, Zhi ; Ha, Grace K ; Kim, Jeremy ; Khosrowzadeh, David ; Petitto, John M</creatorcontrib><description>Research highlights ► More CD3+ T cell in the injured FMN in 52-week-old mice than 8-week-old mice. ► Differences in CD11b+ clusters between 8- and 52-week-old mice in the injured FMN. ► Cumulative neuronal loss did not differ between 8- and 52-week-old mice. ► There was a small reduction in the size of the surviving motor neurons in older mice.</description><identifier>ISSN: 0889-1591</identifier><identifier>EISSN: 1090-2139</identifier><identifier>DOI: 10.1016/j.bbi.2010.08.005</identifier><identifier>PMID: 20727964</identifier><language>eng</language><publisher>Netherlands: Elsevier Inc</publisher><subject>Age ; Aging - physiology ; Allergy and Immunology ; Animals ; Axotomy ; CD11b Antigen - metabolism ; CD3 Complex - metabolism ; Cell Count ; Cell Death - physiology ; Cell Size ; Facial Nerve - pathology ; Facial Nerve - physiology ; Facial nerve axotomy ; Immunohistochemistry ; Male ; Mice ; Mice, Inbred C57BL ; Microglia - immunology ; Motor neuron loss ; Motor Neurons - physiology ; Neurons - pathology ; Perineuronal microglial phagocytic clusters ; Psychiatry ; Resection ; T cells ; T-Lymphocytes - immunology ; Trafficking</subject><ispartof>Brain, behavior, and immunity, 2011-01, Vol.25 (1), p.77-82</ispartof><rights>2010</rights><rights>Published by Elsevier Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c537t-dcc17727ec0e9c3fa0b5c962d1073d9a4952ba5a26197225cce5d5d66b5d02823</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.bbi.2010.08.005$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>230,314,780,784,885,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20727964$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Dauer, Daniel J</creatorcontrib><creatorcontrib>Huang, Zhi</creatorcontrib><creatorcontrib>Ha, Grace K</creatorcontrib><creatorcontrib>Kim, Jeremy</creatorcontrib><creatorcontrib>Khosrowzadeh, David</creatorcontrib><creatorcontrib>Petitto, John M</creatorcontrib><title>Age and facial nerve axotomy-induced T cell trafficking: Relation to microglial and motor neuron status</title><title>Brain, behavior, and immunity</title><addtitle>Brain Behav Immun</addtitle><description>Research highlights ► More CD3+ T cell in the injured FMN in 52-week-old mice than 8-week-old mice. ► Differences in CD11b+ clusters between 8- and 52-week-old mice in the injured FMN. ► Cumulative neuronal loss did not differ between 8- and 52-week-old mice. ► There was a small reduction in the size of the surviving motor neurons in older mice.</description><subject>Age</subject><subject>Aging - physiology</subject><subject>Allergy and Immunology</subject><subject>Animals</subject><subject>Axotomy</subject><subject>CD11b Antigen - metabolism</subject><subject>CD3 Complex - metabolism</subject><subject>Cell Count</subject><subject>Cell Death - physiology</subject><subject>Cell Size</subject><subject>Facial Nerve - pathology</subject><subject>Facial Nerve - physiology</subject><subject>Facial nerve axotomy</subject><subject>Immunohistochemistry</subject><subject>Male</subject><subject>Mice</subject><subject>Mice, Inbred C57BL</subject><subject>Microglia - immunology</subject><subject>Motor neuron loss</subject><subject>Motor Neurons - physiology</subject><subject>Neurons - pathology</subject><subject>Perineuronal microglial phagocytic clusters</subject><subject>Psychiatry</subject><subject>Resection</subject><subject>T cells</subject><subject>T-Lymphocytes - immunology</subject><subject>Trafficking</subject><issn>0889-1591</issn><issn>1090-2139</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkk1v1DAQhi0EosvCD-CCcuOUxR9xEoNUqar4kiohQTmPHHsSvE3sYicr9t_jaEsFHOBkjeedVzPzDCHPGd0xyupX-13XuR2nOabtjlL5gGwYVbTkTKiHZEPbVpVMKnZGnqS0p1khWPuYnHHa8EbV1YYMFwMW2tui18bpsfAYD_njR5jDdCydt4tBW1wXBsexmKPue2dunB9eF59x1LMLvphDMTkTwzCuBqvXlKtjtlpiTqdZz0t6Sh71ekz47O7dkq_v3l5ffiivPr3_eHlxVRopmrm0xrAm94aGojKi17STRtXcMtoIq3SlJO-01LxmquFcGoPSSlvXnbSUt1xsyfnJ93bpJrQGfW56hNvoJh2PELSDPzPefYMhHEBUdSu4ygYv7wxi-L5gmmFyaZ1eewxLgla2Fec8i_-rZJzxWkmRleykzFtKKWJ_3w-jsJKEPWSSsJIE2sLKaUte_D7IfcUvdFnw5iTAvM6DwwjJOPQZl4toZrDB_dP-_K9qMzrvjB5v8IhpH5boMydgkDhQ-LKe0npJLB9RJTKMnxo2xNI</recordid><startdate>20110101</startdate><enddate>20110101</enddate><creator>Dauer, Daniel J</creator><creator>Huang, Zhi</creator><creator>Ha, Grace K</creator><creator>Kim, Jeremy</creator><creator>Khosrowzadeh, David</creator><creator>Petitto, John M</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QG</scope><scope>7T5</scope><scope>7TK</scope><scope>H94</scope><scope>5PM</scope></search><sort><creationdate>20110101</creationdate><title>Age and facial nerve axotomy-induced T cell trafficking: Relation to microglial and motor neuron status</title><author>Dauer, Daniel J ; Huang, Zhi ; Ha, Grace K ; Kim, Jeremy ; Khosrowzadeh, David ; Petitto, John M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c537t-dcc17727ec0e9c3fa0b5c962d1073d9a4952ba5a26197225cce5d5d66b5d02823</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Age</topic><topic>Aging - physiology</topic><topic>Allergy and Immunology</topic><topic>Animals</topic><topic>Axotomy</topic><topic>CD11b Antigen - metabolism</topic><topic>CD3 Complex - metabolism</topic><topic>Cell Count</topic><topic>Cell Death - physiology</topic><topic>Cell Size</topic><topic>Facial Nerve - pathology</topic><topic>Facial Nerve - physiology</topic><topic>Facial nerve axotomy</topic><topic>Immunohistochemistry</topic><topic>Male</topic><topic>Mice</topic><topic>Mice, Inbred C57BL</topic><topic>Microglia - immunology</topic><topic>Motor neuron loss</topic><topic>Motor Neurons - physiology</topic><topic>Neurons - pathology</topic><topic>Perineuronal microglial phagocytic clusters</topic><topic>Psychiatry</topic><topic>Resection</topic><topic>T cells</topic><topic>T-Lymphocytes - immunology</topic><topic>Trafficking</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dauer, Daniel J</creatorcontrib><creatorcontrib>Huang, Zhi</creatorcontrib><creatorcontrib>Ha, Grace K</creatorcontrib><creatorcontrib>Kim, Jeremy</creatorcontrib><creatorcontrib>Khosrowzadeh, David</creatorcontrib><creatorcontrib>Petitto, John M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Animal Behavior Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Brain, behavior, and immunity</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dauer, Daniel J</au><au>Huang, Zhi</au><au>Ha, Grace K</au><au>Kim, Jeremy</au><au>Khosrowzadeh, David</au><au>Petitto, John M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Age and facial nerve axotomy-induced T cell trafficking: Relation to microglial and motor neuron status</atitle><jtitle>Brain, behavior, and immunity</jtitle><addtitle>Brain Behav Immun</addtitle><date>2011-01-01</date><risdate>2011</risdate><volume>25</volume><issue>1</issue><spage>77</spage><epage>82</epage><pages>77-82</pages><issn>0889-1591</issn><eissn>1090-2139</eissn><abstract>Research highlights ► More CD3+ T cell in the injured FMN in 52-week-old mice than 8-week-old mice. ► Differences in CD11b+ clusters between 8- and 52-week-old mice in the injured FMN. ► Cumulative neuronal loss did not differ between 8- and 52-week-old mice. ► There was a small reduction in the size of the surviving motor neurons in older mice.</abstract><cop>Netherlands</cop><pub>Elsevier Inc</pub><pmid>20727964</pmid><doi>10.1016/j.bbi.2010.08.005</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0889-1591 |
| ispartof | Brain, behavior, and immunity, 2011-01, Vol.25 (1), p.77-82 |
| issn | 0889-1591 1090-2139 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_3468329 |
| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Age Aging - physiology Allergy and Immunology Animals Axotomy CD11b Antigen - metabolism CD3 Complex - metabolism Cell Count Cell Death - physiology Cell Size Facial Nerve - pathology Facial Nerve - physiology Facial nerve axotomy Immunohistochemistry Male Mice Mice, Inbred C57BL Microglia - immunology Motor neuron loss Motor Neurons - physiology Neurons - pathology Perineuronal microglial phagocytic clusters Psychiatry Resection T cells T-Lymphocytes - immunology Trafficking |
| title | Age and facial nerve axotomy-induced T cell trafficking: Relation to microglial and motor neuron status |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-26T12%3A24%3A04IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Age%20and%20facial%20nerve%20axotomy-induced%20T%20cell%20trafficking:%20Relation%20to%20microglial%20and%20motor%20neuron%20status&rft.jtitle=Brain,%20behavior,%20and%20immunity&rft.au=Dauer,%20Daniel%20J&rft.date=2011-01-01&rft.volume=25&rft.issue=1&rft.spage=77&rft.epage=82&rft.pages=77-82&rft.issn=0889-1591&rft.eissn=1090-2139&rft_id=info:doi/10.1016/j.bbi.2010.08.005&rft_dat=%3Cproquest_pubme%3E858422268%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=812126953&rft_id=info:pmid/20727964&rft_els_id=S0889159110004307&rfr_iscdi=true |