Crystalline Two-Dimensional DNA-Origami Arrays

Crystalline Two-Dimensional DNA-Origami Arrays

DNA origami gets large: A double‐layer DNA‐origami tile with two orthogonal domains underwent self‐assembly into well‐ordered two‐dimensional DNA arrays with edge dimensions of 2–3 μm (see schematic representation and AFM image). This size is likely to be large enough to connect bottom‐up methods of...

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Veröffentlicht in:Angewandte Chemie International Edition 2011-01, Vol.50 (1), p.264-267
Hauptverfasser: Liu, Wenyan, Zhong, Hong, Wang, Risheng, Seeman, Nadrian C.
Format: Artikel
Sprache:eng
Schlagworte:
Arrays
Crystallization
Deoxyribonucleic acid
DNA
DNA - chemistry
DNA - ultrastructure
DNA origami
Microscopy, Electron, Scanning
Nanostructures - chemistry
Nanostructures - ultrastructure
nanotechnology
Nucleic Acid Conformation
Oligonucleotide Array Sequence Analysis - methods
scanning probe microscopy
self-assembly
two-dimensional arrays
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Zusammenfassung:DNA origami gets large: A double‐layer DNA‐origami tile with two orthogonal domains underwent self‐assembly into well‐ordered two‐dimensional DNA arrays with edge dimensions of 2–3 μm (see schematic representation and AFM image). This size is likely to be large enough to connect bottom‐up methods of patterning with top‐down approaches.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201005911