Relationship between free iron and glycated hemoglobin in uncontrolled type 2 diabetes patients associated with complications

Relationship between free iron and glycated hemoglobin in uncontrolled type 2 diabetes patients associated with complications

Free iron in serum has been found in several disease conditions including diabetes. In the present work, we studied the relationship between free iron, fasting blood glucose (FBG) and glycated haemoglobin (HbA 1c ). Study was carried out on 50 type 2 diabetes cases under poor glycemic control associ...

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Veröffentlicht in:Indian journal of clinical biochemistry 2008, Vol.23 (1), p.67-70
Hauptverfasser: Shetty, Jeevan K., Prakash, Mungli, Ibrahim, Mohammad S.
Format: Artikel
Sprache:eng
Schlagworte:
Biochemistry
Biomedical and Life Sciences
Chemistry/Food Science
Diabetes
Hemoglobin
Iron
Life Sciences
Microbiology
Pathology
Studies
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Zusammenfassung:Free iron in serum has been found in several disease conditions including diabetes. In the present work, we studied the relationship between free iron, fasting blood glucose (FBG) and glycated haemoglobin (HbA 1c ). Study was carried out on 50 type 2 diabetes cases under poor glycemic control associated with complications, 53 type 2 diabetes cases under good glycemic control and 40 healthy controls. We estimated free iron, both ferrous (Fe +2 ) and ferric (Fe +3 ) form, protein thiols, lipid hydroperoxides, FBG, HbA1c and serum ferritin levels in serum. There was a significant increase in free iron in Fe +3 state (p
ISSN:0970-1915
0974-0422
DOI:10.1007/s12291-008-0016-4