Prochlorperazine versus cinnarizine in cases of vertigo

Cases of vertigo comprised 1.82% of Ear, Nose & Throat out patient cases. Peripheral lesion as a cause of vertigo was seen in 51.12%. Meniere's disease and Benign Paroxysmal Positional Vertigo (BPPV) were found to be the common causes comprising 21.80% and 15.78% of total cases of vertigo. Central lesion as a cause of vertigo was seen in 48.87% of cases. Vertebre Basilar Insufficiency (VBI) was the commonest cause of central lesion seen in 20.30% of cases. An equal number of cases, selected randomly, underwent treatment with prochlorperazine ± Head Balance exercises and Cinnarizine ± Head Balance exercises. At the end of 5 weeks of treatment there was 100% subjective improvement with prochlorperazine group and 97.14% in the group with cinnarizine. Side effects were noted in 34.00% of cases; of these 23.00% were seen in cinnarizine group and 11.00% in prochlorperazine. Drowsiness was the commonest side effect and was statistically more significant with cinnarzine group. Response to the treatment was significantly more in cases with vertigo of peripheral origin as compared with vertigo of central origin.