Use of mitomycin C in endo-DCR

To evaluate the role of topical Mitomycin C in Endoscopic Dacryocystorhinostomy (DCR), for the prevention of stomal stenosis. Thirty patients undergoing endoscopic DCR for chronic dacryocystitis were studied prospectively. The follow up period was 12 months. PATIENTS were divided into two groups randomly. All of them underwent endoscopic DCR. One group was subjected to topical Mitomycin C application after surgery while the control group was not. Postoperative relief of epiphora and endoscopic documentation of the patency of the stoma were the main outcome measures. 80% cases of the Mitomycin C group and 86.67% cases of the non Mitomycin C group had long-term successful results. This result is not statistically significant (p> 0.2). Intraoperative Mitomycin C application does not alter the long-term results in endoscopic DCR. A properly and adequately performed surgery is more vital for successful result.