Salivary and serum interleukin 1 beta, interleukin 6 and tumor necrosis factor alpha in patients with leukoplakia and oral cancer

The aim of study was to compare salivary and serum concentrations of interleukin 1 beta (IL-1β), interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α) in patients with oral leukoplakia, oral cancer and healthy controls. Eighty eight patients (28 with oral cancer, 29 leukoplakia, and 31 health...

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Veröffentlicht in:	Medicina oral, patología oral y cirugía bucal patología oral y cirugía bucal, 2012-01, Vol.17 (1), p.e10-e15
Hauptverfasser:	Brailo, Vlaho, Vucicevic-Boras, Vanja, Lukac, Josip, Biocina-Lukenda, Dolores, Zilic-Alajbeg, Iva, Milenovic, Aleksandar, Balija, Melita
Format:	Artikel
Sprache:	eng
Schlagworte:	Dentistry Female Humans Interleukin-1beta - analysis Interleukin-1beta - blood Interleukin-6 - analysis Interleukin-6 - blood Leukoplakia, Oral - blood Male Middle Aged Mouth Neoplasms - blood Oral Medicine and Pathology Saliva - chemistry Tumor Necrosis Factor-alpha - analysis Tumor Necrosis Factor-alpha - blood
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Zusammenfassung:	The aim of study was to compare salivary and serum concentrations of interleukin 1 beta (IL-1β), interleukin 6 (IL-6) and tumor necrosis factor alpha (TNF-α) in patients with oral leukoplakia, oral cancer and healthy controls. Eighty eight patients (28 with oral cancer, 29 leukoplakia, and 31 healthy controls) were included in this study. Cytokine concentrations were measured by commercial enzyme linked immunoassay. Salivary IL-1β and IL-6 were significantly higher in oral cancer patients than in patients with leukoplakia and control group (p
ISSN:	1698-6946 1698-4447 1698-6946
DOI:	10.4317/medoral.17323